Monitor Intently (one)belzutifan will reduce the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism.lumefantrine will reduce the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.buprenorphine, very long-acting injection and diazepam both maximize